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International Association Against Painful Experiments on Animals

101 Misleading results from Vivisection Animal Experiments

10: Rabbit Test Misses Human Eye Irritant

Lindane is probably best known as an agricultural insecticide but very dilute lotions, creams and shampoos are used therapeutically for treating lice and scabies. Nevertheless such preparations can cause “excessive eye irritation” and conjunctivitis,1 and the British National Formulary (1993) warns users to “avoid contact with eyes”. In rabbits, however, application of a far more concentrated solution produced only minimal effects.(1) Furthermore, exposure to lindane in the form of a dust proved non-irritating to the eyes and nasal mucosa of rabbits but caused irritation to the eyes and respiratory passages of sensitive people.(1)

References

1) W.M.Grant, Toxicology of the Eye, 2nd edition (Charles Thomas, 1974).

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