The success of selenium disulphide (Selsun) as an antidandruff shampoo, led to the suggestion that it might also be useful for the treatment of blepharitis, a similar but painful condition involving the eyelids. Trials were carried out in which an ointment containing 0.5% selenium disulphide was applied to the lid margins. However, the ointment proved irritating if it accidentally came into contact with the conjunctiva and one patient developed "moderately severe conjunctivitis."(1) In contrast, animal experiments have shown that "Selenium disulphide 0.5% ophthalmic ointment is nontoxic to rabbit corneas or conjunctivas" (emphasis added).(2)
1) G.C.Bahn, Southern Medical Journal, 1954, vol.47, 749-752.
2) J.W.Rosenthal & H.Adler, Southern Medical Journal, 1962, March, 318.
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