Squalene is a natural constituent of human sebum, the substance formed by sebaceous glands around the roots of hairs to keep the skin lubricated and supple. Although a natural human product, squalene has still been applied to the skin of rabbits and guinea pigs, where it actually produced hair loss. This is obviously not the case in people,(1) and it has been extensively and safely employed in cosmetics.(2)
1) B.Boughton et al, Journal of Investigative Dermatology, 1955, vol.24 179-189.
2) M M Rieger & G W Battista, Journal of the Society of Cosmetic Chemists, 1964, vol 15, 161-177
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