International Association Against Painful Experiments on Animals

101 Misleading results from Vivisection Animal Experiments

4: Suprofen Joins Band List

The arthritis drug suprofen (Suprol) was withdrawn worldwide in May 1987 following reports of kidney problems and pain in the side of the body.(1) Patients experiencing these side-effects had to have their kidney function monitored for 2 years after they stopped taking the drug.(2) The dangers were unexpected because "In animal studies suprofen has been shown to have an excellent safety profile. No significant effects were observed on cardiac, renal [kidney] or central nervous system parameters in several species."(3)


1) Drug Withdrawal from Sale, C.Spriet-Pourra & M.Auriche (PJB Publications, 1988)
2) FDA Drug Review: Postapproval Risks 1976-1985 (US General Accounting Offce, April 1990).
3) A.Yeadon et al, Pharmacology, 1983, vol.27, Suppl.l, 87-94.

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